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1

Transport of Lamivudine [(-)- -L-2',3'-Dideoxy-3'-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3

Minuesa, G., Volk, C., Molina-Arcas, M., Gorboulev, V., Erkizia, I., Arndt, P., Clotet, B., Pastor-Anglada, M., Koepsell, H., Martinez-Picado, J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2009

Language:

english

File:

PDF, 549 KB

english, 2009

2

Development of combination therapies to maximize the impact of KRAS-G12C inhibitors in lung cancer

Molina-Arcas, Miriam, Moore, Christopher, Rana, Sareena, van Maldegem, Febe, Mugarza, Edurne, Romero-Clavijo, Pablo, Herbert, Eleanor, Horswell, Stuart, Li, Lian-Sheng, Janes, Matthew R., Hancock, Dav

Journal:

Science Translational Medicine

Year:

2019

Language:

english

File:

PDF, 2.25 MB

english, 2019

3

Nucleoside transporters in chronic lymphocytic leukaemia

Pastor-Anglada, M, Molina-Arcas, M, Casado, F J, Bellosillo, B, Colomer, D, Gil, J

Journal:

Year:

2004

Language:

english

File:

PDF, 134 KB

english, 2004

4

Equilibrative nucleoside transporter-2 (hENT2) protein expression correlates with ex vivo sensitivity to fludarabine in chronic lymphocytic leukemia (CLL) cells

Molina-Arcas, M, Marcé, S, Villamor, N, Huber-Ruano, I, Casado, F J, Bellosillo, B, Montserrat, E, Gil, J, Colomer, D, Pastor-Anglada, M

Journal:

Year:

2004

Language:

english

File:

PDF, 158 KB

english, 2004

5

Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5′-DFUR in breast cancer MCF7 cells

Míriam Molina-Arcas, Gema Moreno-Bueno, Pedro Cano-Soldado, Héctor Hernández-Vargas, F. Javier Casado, José Palacios, Marçal Pastor-Anglada

Journal:

Biochemical Pharmacology

Year:

2006

Language:

english

File:

PDF, 886 KB

english, 2006

6

Compensatory effects of the human nucleoside transporters on the response to nucleoside-derived drugs in breast cancer MCF7 cells

Pedro Cano-Soldado, Míriam Molina-Arcas, Berta Algueró, Ignacio Larráyoz, M. Pilar Lostao, Anna Grandas, F.Javier Casado, Marçal Pastor-Anglada

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 456 KB

english, 2008

7

How to Fool a Wonder Drug: Truncate and Dimerize

Miriam Molina-Arcas, Julian Downward

Journal:

Year:

2012

Language:

english

File:

PDF, 249 KB

english, 2012

8

The GATA2 Transcriptional Network Is Requisite for RAS Oncogene-Driven Non-Small Cell Lung Cancer

Madhu S. Kumar, David C. Hancock, Miriam Molina-Arcas, Michael Steckel, Phillip East, Markus Diefenbacher, Elena Armenteros-Monterroso, François Lassailly, Nik Matthews, Emma Nye, Gordon Stamp, Axel B

Journal:

Year:

2012

Language:

english

File:

PDF, 1.80 MB

english, 2012

9

Cell entry and export of nucleoside analogues

Marçal Pastor-Anglada, Pedro Cano-Soldado, Míriam Molina-Arcas, M. Pilar Lostao, Ignacio Larráyoz, Javier Martínez-Picado, F. Javier Casado

Journal:

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

10

567 USEFULNESS OF MICROFLUIDIC CARDS TO PREDICT RESISTANCE TO ANTICANCER CHEMOTHERAPY IN LIVER TUMOURS

E. Lozano, P. Martinez-Becerra, M.A. Serrano, M.R. Romero, N. Grañne, L. Trigueros-Motos, A. Del Rio, I. Monte, F.J. Casado, M. Molina-Arcas, L. Alvarez, L. Muñnoz-Bellvis, M. Pastor-Anglada, J.J.G. M

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

11

Aquaporin 3 (AQP3) participates in the cytotoxic response to nucleoside-derived drugs

Laia Trigueros-Motos, Sandra Pérez-Torras, F Javier Casado, Míriam Molina-Arcas, Marçal Pastor-Anglada

Journal:

Year:

2012

Language:

english

File:

PDF, 467 KB

english, 2012

12

Physiological and Pharmacological Roles of Nucleoside Transporter Proteins

Molina-Arcas, Míriam, Trigueros-Motos, Laia, Casado, F. Javier, Pastor-Anglada, Marçal

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2008

Language:

english

File:

PDF, 106 KB

english, 2008

13

Determination of synthetic lethal interactions in KRAS oncogene-dependent cancer cells reveals novel therapeutic targeting strategies

Steckel, Michael, Molina-Arcas, Miriam, Weigelt, Britta, Marani, Michaela, Warne, Patricia H, Kuznetsov, Hanna, Kelly, Gavin, Saunders, Becky, Howell, Michael, Downward, Julian, Hancock, David C

Journal:

Year:

2012

Language:

english

File:

PDF, 2.26 MB

english, 2012

14

The Human Concentrative Nucleoside Transporter-3 C602R Variant Shows Impaired Sorting to Lipid Rafts and Altered Specificity for Nucleoside-Derived Drugs

Errasti-Murugarren, E., Molina-Arcas, M., Casado, F. J., Pastor-Anglada, M.

Journal:

Molecular Pharmacology

Year:

2010

Language:

english

File:

PDF, 926 KB

english, 2010

15

Coordinate Direct Input of Both KRAS and IGF1 Receptor to Activation of PI3 kinase in KRAS-Mutant Lung Cancer

Molina-Arcas, M., Hancock, D. C., Sheridan, C., Kumar, M. S., Downward, J.

Journal:

Cancer Discovery

Year:

2013

Language:

english

File:

PDF, 3.15 MB

english, 2013

16

A splice variant of the SLC28A3 gene encodes a novel human concentrative nucleoside transporter-3 (hCNT3) protein localized in the endoplasmic reticulum

Errasti-Murugarren, E., Molina-Arcas, M., Casado, F. J., Pastor-Anglada, M.

Journal:

The FASEB Journal

Year:

2009

Language:

english

File:

PDF, 426 KB

english, 2009

17

Identification of TIGAR in the equilibrative nucleoside transporter 2-mediated response to fludarabine in chronic lymphocytic leukemia cells

Lopez-Guerra, M., Trigueros-Motos, L., Molina-Arcas, M., Villamor, N., Casado, F. J., Montserrat, E., Campo, E., Colomer, D., Pastor-Anglada, M.

Journal:

Year:

2008

Language:

english

File:

PDF, 424 KB

english, 2008

18

Expression and Functionality of Anti-Human Immunodeficiency Virus and Anticancer Drug Uptake Transporters in Immune Cells

Minuesa, G., Purcet, S., Erkizia, I., Molina-Arcas, M., Bofill, M., Izquierdo-Useros, N., Casado, F. J., Clotet, B., Pastor-Anglada, M., Martinez-Picado, J.

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2007

Language:

english

File:

PDF, 511 KB

english, 2007

19

Role of Nucleoside Transporters in Nucleoside-Derived Drug Sensitivity

Molina-Arcas, M., Pastor-Anglada, M.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2010

Language:

english

File:

PDF, 118 KB

english, 2010

20

Identification of new combination therapies for NSCLC tumours harbouring KRAS mutations

Molina-Arcas, M., Hancock, D.C., Moore, C., Horswell, S., Matthews, N., Downward, J.

Journal:

European Journal of Cancer

Year:

2016

Language:

english

File:

PDF, 59 KB

english, 2016

21

RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression

Castellano, Esther, Molina-Arcas, Miriam, Krygowska, Agata Adelajda, East, Philip, Warne, Patricia, Nicol, Alastair, Downward, Julian

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 1.47 MB

english, 2016

22

Oncogenic RAS Signaling Promotes Tumor Immunoresistance by Stabilizing PD-L1 mRNA

Coelho, Matthew A., de Carné Trécesson, Sophie, Rana, Sareena, Zecchin, Davide, Moore, Christopher, Molina-Arcas, Miriam, East, Philip, Spencer-Dene, Bradley, Nye, Emma, Barnouin, Karin, Snijders, Amb

Journal:

Year:

2017

Language:

english

File:

PDF, 2.99 MB

english, 2017

23

IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche

Wamaitha, Sissy E., Grybel, Katarzyna J., Alanis-Lobato, Gregorio, Gerri, Claudia, Ogushi, Sugako, McCarthy, Afshan, Mahadevaiah, Shantha K., Healy, Lyn, Lea, Rebecca A., Molina-Arcas, Miriam, Devito,

Journal:

Nature Communications

Year:

2020

File:

PDF, 2.67 MB

2020

24

[BMJ Publishing Group Ltd Abstracts of the 25th Biennial Congress of the European Association for Cancer Research, Amsterdam, The Netherlands, 30 June â 3 July 2018 - ()] Oral Presentations - 15âIdentification of new combination therapies for lung cancer tumours harbouring KRAS mutations

Molina-Arcas, M, Moore, C, Rana, S, Van Maldegem, F, Horswell, S, Hancock, D, Downward, J

File:

PDF, 70 KB

25

RAS orchestrates an increase of interstitial adenosine in lung adenocarcinoma to promote immune evasion

de CarnÃ© TrÃ©cesson, S., Boumhela, J., Moore, C., Caswell, D., Mugarza-Strobl, E., Molina-Arcas, M., Smith, P., Sachsenmeier, K., East, P., Downward, J.

Journal:

European Journal of Cancer

Year:

2020

File:

PDF, 1.58 MB

2020

26

Targeting oncogenic signalling pathways to modulate the lung cancer immune microenvironment

Van Maldegem, F., Mugarza, E., Molina-Arcas, M., Valand, K., Rana, S., Cole, M., Romero-Clavijo, P., Boumelha, J., Moore, C., Downward, J.

Journal:

European Journal of Cancer

Year:

2020

File:

PDF, 64 KB

2020